Chloride → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(6-ethyl-pyridine-3-carbonyl)-1H-quinolin-4-one

HRID 946568Notes

Reaction equation

HRID 946568 reaction equation
[CH2:26]([CH3:27])[c:28]1[n:29][cH:30][c:31]([I:34])[cH:32][cH:33]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([Br:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[CH3:25].[CH:36]([Mg+:37])([CH3:38])[CH3:39].[Cl-:35]>>[C:4](=[O:5])([c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([Br:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[c:31]1[cH:30][n:29][c:28]([CH2:26][CH3:27])[cH:33][cH:32]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 577545321-(6-Bromo-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid methoxy-methyl-amideHCID 668794762-Ethyl-5-iodo-pyridineHCID 178461726HCID 178461726, compound

Product 1

HCID 577545051-(6-Bromo-pyridin-2-ylmethyl)-3-(6-ethyl-pyridine-3-carbonyl)-1H-quinolin-4-one

Sources & evidence

ORD record
ord-793d7384ccff45ffaac743caddf51f0b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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