Triethylamine → Ethyl 6-[(2,2,4,4-tetramethyl-thiochroman-6-yl)ethynyl]nicotinate

HRID 947238Notes

Reaction equation

[CH3:1][C:2]1([CH3:16])[S:3][c:4]2[cH:5][cH:6][c:7]([C:14]#[CH:15])[cH:8][c:9]2[C:10]([CH3:12])([CH3:13])[CH2:11]1.[CH3:71][CH2:72][N:73]([CH2:74][CH3:75])[CH2:76][CH3:77].[Cl:17][c:18]1[n:19][cH:20][c:21]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[cH:27][cH:28]1.[I-:29].[Pd:30]([Cl:31])[Cl:32].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[CH3:1][C:2]1([CH3:16])[S:3][c:4]2[cH:5][cH:6][c:7]([C:14]#[C:15][c:18]3[n:19][cH:20][c:21]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[cH:27][cH:28]3)[cH:8][c:9]2[C:10]([CH3:12])([CH3:13])[CH2:11]1