Ammonium → 1,8-Bis-dimethylamino-3-(2,4,6-trimethyl-phenyl)-1,8-diaza-spiro[4.5]decane-2,4-dione

HRID 947267Notes

Reaction equation

HRID 947267 reaction equation
[CH3:1][O:2][C:3](=[O:4])[C:5]1([N:14]([N:15]([CH3:16])[CH3:17])[C:18]([CH2:19][c:20]2[c:21]([CH3:28])[cH:22][c:23]([CH3:27])[cH:24][c:25]2[CH3:26])=[O:29])[CH2:6][CH2:7][N:8]([N:11]([CH3:12])[CH3:13])[CH2:9][CH2:10]1.[CH3:30][C:31]([CH3:32])([O-:33])[CH3:34].[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[ClH:38].[K+:35].[NH4+:36].[OH-:37]>>[O:2]=[C:3]1[C:5]2([CH2:6][CH2:7][N:8]([N:11]([CH3:12])[CH3:13])[CH2:9][CH2:10]2)[N:14]([N:15]([CH3:16])[CH3:17])[C:18](=[O:29])[CH:19]1[c:20]1[c:21]([CH3:28])[cH:22][c:23]([CH3:27])[cH:24][c:25]1[CH3:26]

Participants

8

Reactant 7

HCID 223AmmoniumHCID 313Hydrochloric AcidHCID 813Potassium CationHCID 961HydroxideHCID 6228DimethylformamideHCID 45749132-Methylpropan-2-olateHCID 672274551-Dimethylamino-4-{N',N'-dimethyl-N-[2-(2,4,6-trimethyl-phenyl)-acetyl]-hydrazino}-piperidine-4-carboxylic acid methyl ester

Product 1

HCID 682286451,8-Bis-dimethylamino-3-(2,4,6-trimethyl-phenyl)-1,8-diaza-spiro[4.5]decane-2,4-dione

Sources & evidence

ORD record
ord-ea64027adaa5419f813a870c3986c616
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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