4-Chlorophenol → 2-(4-Chlorophenoxy)-1,3-difluoro-5-nitrobenzene

HRID 947443Notes

Reaction equation

HRID 947443 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[Cs+:25].[Cs+:26].[F:1][c:2]1[cH:3][c:4]([N+:10](=[O:11])[O-:12])[cH:5][c:6]([F:9])[c:7]1[F:8].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[OH:13][c:14]1[cH:15][cH:16][c:17]([Cl:18])[cH:19][cH:20]1>>[F:1][c:2]1[cH:3][c:4]([N+:10](=[O:11])[O-:12])[cH:5][c:6]([F:9])[c:7]1[O:13][c:14]1[cH:15][cH:16][c:17]([Cl:18])[cH:19][cH:20]1

Participants

6

Reactant 5

HCID 46844-ChlorophenolHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 27827931,2,3-Trifluoro-5-nitrobenzene

Product 1

HCID 469415962-(4-Chlorophenoxy)-1,3-difluoro-5-nitrobenzene

Sources & evidence

ORD record
ord-f0f16d5f7d20430fb5379ac61723a778
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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