Hydroxide → 1-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid

HRID 947522Notes

Reaction equation

HRID 947522 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8](=[O:24])[n:9]([CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[cH:10]1.[Li+:28].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1.[OH-:27].[OH2:25].[OH2:26]>>[O:3]=[C:4]([OH:5])[c:6]1[nH:7][c:8](=[O:24])[n:9]([CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[cH:10]1

Participants

6

Reactant 5

HCID 961HydroxideHCID 962Water2×HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 59006357Tert-butyl 4-(4-(ethoxycarbonyl)-2-oxo-2,3-dihydroimidazol-1-yl)piperidine-1-carboxylate

Product 1

HCID 590063701-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid

Sources & evidence

ORD record
ord-ffe41617441942d8b3dd85fb2cd54905
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…