Potassium Cation → Ethyl 2-(4-isopropoxy-3-nitrophenyl)-4-methyl-5-thiazolecarboxylate

HRID 948085Notes

Reaction equation

HRID 948085 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[CH:28]([CH3:29])([CH3:30])[Br:31].[K+:26].[K+:27].[OH2:32].[OH:1][c:2]1[c:3]([N+:19](=[O:20])[O-:21])[cH:4][c:5](-[c:8]2[s:9][c:10]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:11]([CH3:13])[n:12]2)[cH:6][cH:7]1>>[O:1]([c:2]1[c:3]([N+:19](=[O:20])[O-:21])[cH:4][c:5](-[c:8]2[s:9][c:10]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:11]([CH3:13])[n:12]2)[cH:6][cH:7]1)[CH:28]([CH3:29])[CH3:30]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 63582-BromopropaneHCID 19660Carbonate IonHCID 135737466Ethyl 2-(4-hydroxy-3-nitrophenyl)-4-methylthiazole-5-carboxylate

Product 1

HCID 19965110Ethyl 2-(4-isopropoxy-3-nitrophenyl)-4-methyl-5-thiazolecarboxylate

Sources & evidence

ORD record
ord-bdd728db0f1a42cb9af88e23e3f54452
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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