Acetonitrile → 4-(2,4-Dimethoxy-3-nitro-phenylethynyl)-1-methyl-1H-pyrazole

HRID 948107Notes

Reaction equation

HRID 948107 reaction equation
[C:15](#[CH:16])[c:17]1[cH:18][n:19][n:20]([CH3:22])[cH:21]1.[CH3:1][O:2][c:3]1[c:4]([I:14])[cH:5][cH:6][c:7]([O:12][CH3:13])[c:8]1[N+:9](=[O:10])[O-:11].[CH3:23][C:24]#[N:25].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[Cu:26][I:27]>>[CH3:1][O:2][c:3]1[c:4]([C:16]#[C:15][c:17]2[cH:18][n:19][n:20]([CH3:22])[cH:21]2)[cH:5][cH:6][c:7]([O:12][CH3:13])[c:8]1[N+:9](=[O:10])[O-:11]

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 511383214-Ethynyl-1-methyl-1H-pyrazoleHCID 574219462,4-Dimethoxy-3-nitro-iodobenzene

Product 1

HCID 687741874-(2,4-Dimethoxy-3-nitro-phenylethynyl)-1-methyl-1H-pyrazole

Sources & evidence

ORD record
ord-3ad0e887e40947d29fb437df77dce04f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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