1,2-Dichloroethane → N-(2-amino-3-bromo-6-methoxy-phenyl)-4-isopropyl-benzamide

HRID 948204Notes

Reaction equation

HRID 948204 reaction equation
[Br:1][c:2]1[c:3]([NH2:11])[c:4]([NH2:10])[c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH2:12]([Cl:13])[CH2:14][Cl:15].[CH3:28][N:29]([c:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1)[CH3:36].[CH:16]([CH3:17])([CH3:18])[c:19]1[cH:20][cH:21][c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27]1.[Cl:37][CH2:38][Cl:39]>>[Br:1][c:2]1[c:3]([NH2:11])[c:4]([NH:10][C:23]([c:22]2[cH:21][cH:20][c:19]([CH:16]([CH3:17])[CH3:18])[cH:27][cH:26]2)=[O:24])[c:5]([O:8][CH3:9])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 6344DichloromethaneHCID 108204-Isopropylbenzoic AcidHCID 142844-(Dimethylamino)pyridineHCID 577720123-Bromo-6-methoxybenzene-1,2-diamine

Product 1

HCID 57772045N-(2-amino-3-bromo-6-methoxy-phenyl)-4-isopropyl-benzamide

Sources & evidence

ORD record
ord-3b79e9f0059f408abd469f849eddde16
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…