Dimethylformamide → 2-Chloro-5-bromo-6-fluorobenzamide

HRID 948429Notes

Reaction equation

HRID 948429 reaction equation

[Cl:13][C:14]([C:15]([Cl:16])=[O:17])=[O:18].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[c:7]([F:12])[c:8]([Br:11])[cH:9][cH:10]1.[Cl:24][CH2:25][Cl:26].[O:19]=[CH:20][N:21]([CH3:22])[CH3:23]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH2:21])[c:7]([F:12])[c:8]([Br:11])[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 6228Dimethylformamide

HCID 6344Dichloromethane

HCID 65578Oxalyl chloride

HCID 217423273-Bromo-6-chloro-2-fluorobenzoic acid

Product 1

HCID 184515062-Chloro-5-bromo-6-fluorobenzamide

Sources & evidence

ORD record: ord-999864e4473b4a5bbd92495b1e90e58b
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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