Chloride → 4-chloro-N-[5-chloro-2-(2-chloro-3-methyl-benzoyl)-pyridin-3-yl]-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide

HRID 948534Notes

Reaction equation

HRID 948534 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH:28]([Mg+:29])([CH3:30])[CH3:31].[Cl-:27].[Cl:32][c:33]1[c:34]([C:35](=[O:36])[N:37]([O:38][CH3:39])[CH3:40])[cH:41][cH:42][cH:43][c:44]1[CH3:45]>>[c:2]1([C:35]([c:34]2[c:33]([Cl:32])[c:44]([CH3:45])[cH:43][cH:42][cH:41]2)=[O:36])[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25]

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 539138242-Chloro-N-methoxy-N,3-dimethylbenzamideHCID 57942086N-(2-Bromo-5-chloro-pyridin-3-yl)-4-chloro-N-methoxvmethyl-3-trifluoromethyl-benzenesulfonamideHCID 178461726HCID 178461726, compound

Product 1

HCID 579422364-chloro-N-[5-chloro-2-(2-chloro-3-methyl-benzoyl)-pyridin-3-yl]-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-349cd6412998496cbcad30a1da4d6994
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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