Ethanol → N-[4-(2-methoxybenzyloxy)-phenyl]-N'-methyl-N'-methoxyurea

HRID 948557Notes

Reaction equation

HRID 948557 reaction equation
[CH3:20][O:21][c:22]1[c:23]([CH2:24][Cl:25])[cH:26][cH:27][cH:28][cH:29]1.[CH3:2][CH2:3][O-:4].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[CH3:36][CH2:37][OH:38].[Na+:1].[Na:5].[OH2:35].[OH:6][c:7]1[cH:8][cH:9][c:10]([NH:13][C:14](=[O:15])[N:16]([O:17][CH3:18])[CH3:19])[cH:11][cH:12]1>>[O:6]([c:7]1[cH:8][cH:9][c:10]([NH:13][C:14](=[O:15])[N:16]([O:17][CH3:18])[CH3:19])[cH:11][cH:12]1)[CH2:24][c:23]1[c:22]([O:21][CH3:20])[cH:29][cH:28][cH:27][cH:26]1

Participants

9

Reactant 8

HCID 702EthanolHCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 814952-(Chloromethyl)anisoleHCID 1194401-Hydroxyethyl radicalHCID 5360545SodiumHCID 13254818N'-(4-Hydroxyphenyl)-N-methoxy-N-methylurea

Product 1

HCID 12893515N-[4-(2-methoxybenzyloxy)-phenyl]-N'-methyl-N'-methoxyurea

Sources & evidence

ORD record
ord-d92ffe8da1274260840d1e3d3c601d80
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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