Dimethylformamide → 6-Chloro-1,2,3,4-tetrahydroquinoline

HRID 948600Notes

Reaction equation

[Cl:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[NH:9]1[CH2:10][CH2:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]21.[O:19]=[CH:20][N:21]([CH3:22])[CH3:23]>>[Cl:1][c:15]1[cH:14][c:13]2[c:18]([cH:17][cH:16]1)[NH:9][CH2:10][CH2:11][CH2:12]2

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 31398Chlorosuccinimide

HCID 694601,2,3,4-Tetrahydroquinoline

Product 1

HCID 111828396-Chloro-1,2,3,4-tetrahydroquinoline

Sources & evidence

ORD record: ord-627edc3add93451aa131fec3c6e74324
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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