p-Anisoyl chloride → Benzyl 3-[1-(4-methoxybenzoyl)-5-oxo-2-pyrrolidinyl]propanoate

HRID 948655Notes

Reaction equation

HRID 948655 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([CH2:10][CH2:11][CH:12]1[NH:13][C:14](=[O:17])[CH2:15][CH2:16]1)=[O:18].[CH3:19][O:20][c:21]1[cH:22][cH:23][c:24]([C:25](=[O:26])[Cl:27])[cH:28][cH:29]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([CH2:10][CH2:11][CH:12]1[N:13]([C:25]([c:24]2[cH:23][cH:22][c:21]([O:20][CH3:19])[cH:29][cH:28]2)=[O:26])[C:14](=[O:17])[CH2:15][CH2:16]1)=[O:18]

Participants

5

Reactant 4

HCID 7477p-Anisoyl chlorideHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 15588871Benzyl 3-(5-oxopyrrolidin-2-YL)propanoate

Product 1

HCID 15588878Benzyl 3-[1-(4-methoxybenzoyl)-5-oxo-2-pyrrolidinyl]propanoate

Sources & evidence

ORD record
ord-68a699209346420da466fc49b238efca
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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