Tetrahydrofuran → (+)-3,4-dihydro-5-methyl-2-[1-(5-methyl-1-trityl-1H-imidazol-4-yl)ethyl]pyrimido[1,6-a]indol-1(2H)-one
Reaction equation
[CH3:1][c:2]1[c:3]([CH2:11][CH2:12][NH:13][CH:14]([CH3:15])[c:16]2[n:17][cH:18][n:19]([C:22]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)([c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[c:20]2[CH3:21])[nH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12.[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[O:41]1[CH2:42][CH2:45][CH2:44][CH2:43]1>>[CH3:1][c:2]1[c:3]2[n:4]([c:5]3[cH:6][cH:7][cH:8][cH:9][c:10]13)[C:42](=[O:41])[N:13]([CH:14]([CH3:15])[c:16]1[n:17][cH:18][n:19]([C:22]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)([c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[c:20]1[CH3:21])[CH2:12][CH2:11]2Participants
4
Sources & evidence
- ORD record
- ord-8c6b997a63384c14966e898f17cd044e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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