Potassium Cation → 8-Difluoromethoxy-3-iodo-2-phenyl-pyrano[2,3-c]pyridin-4-one

HRID 949005Notes

Reaction equation

HRID 949005 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[Cl:1][CH:2]([F:3])[F:4].[I:5][c:6]1[c:7](=[O:23])[c:8]2[c:9]([c:10](=[O:14])[nH:11][cH:12][cH:13]2)[o:15][c:16]1-[c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1.[K+:28].[K+:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[CH:2]([F:3])([F:4])[O:14][c:10]1[c:9]2[c:8]([c:7](=[O:23])[c:6]([I:5])[c:16](-[c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[o:15]2)[cH:13][cH:12][n:11]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 6372ChlorodifluoromethaneHCID 19660Carbonate IonHCID 866710193-iodo-2-phenyl-7H-pyrano[2,3-c]pyridine-4,8-dione

Product 1

HCID 670676838-Difluoromethoxy-3-iodo-2-phenyl-pyrano[2,3-c]pyridin-4-one

Sources & evidence

ORD record
ord-a0581080a2ac43a6a7c29b86c91376c9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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