Hydrochloric Acid → N-(4-chlorophenyl)-4-cyano-4-phenylpiperidine-1-carbothioamide

HRID 949030Notes

Reaction equation

HRID 949030 reaction equation
[C:19](#[N:20])[C:21]1([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:33][CH2:34][Cl:35].[Cl:8][c:9]1[cH:10][cH:11][c:12]([N:15]=[C:16]=[S:17])[cH:13][cH:14]1.[ClH:18]>>[Cl:8][c:9]1[cH:10][cH:11][c:12]([NH:15][C:16](=[S:17])[N:24]2[CH2:23][CH2:22][C:21]([C:19]#[N:20])([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:26][CH2:25]2)[cH:13][cH:14]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 164804-Chlorophenyl isothiocyanateHCID 1811384-Piperidinecarbonitrile, 4-phenyl-

Product 1

HCID 3875011N-(4-chlorophenyl)-4-cyano-4-phenylpiperidine-1-carbothioamide

Sources & evidence

ORD record
ord-9761d7e1f2924154951f59f5e29a9cfa
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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