Indole → Indoline

HRID 950014Notes

Reaction equation

HRID 950014 reaction equation
[C:11](=[O:12])([O-:13])[O-:14].[K+:15].[K+:16].[NH2:1][c:2]1[c:3]([CH2:8][CH2:9][OH:10])[cH:4][cH:5][cH:6][cH:7]1.[nH:17]1[c:18]2[c:19]([cH:20][cH:21][cH:22][cH:23]2)[cH:24][cH:25]1>>[NH:1]1[c:2]2[c:3]([cH:4][cH:5][cH:6][cH:7]2)[CH2:8][CH2:9]1

Participants

5

Reactant 4

HCID 798IndoleHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 79282o-Aminophenethyl alcohol

Product 1

HCID 10328Indoline

Sources & evidence

ORD record
ord-0ccd130205eb4dc8b19f0e2add72321b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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