1,1-Dibromoethane → 3-(1-triisopropylsilanyl-1H-indol-5-yl)-azetidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:6][CH:7]([Br:8])[CH3:9].[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH:19]([I:21])[CH2:20]1.[CH3:42][C:43]([N:44]([CH3:45])[CH3:46])=[O:47].[Cl:1][C:2]([SiH3:3])([Cl:4])[Cl:5].[Cu:49][I:50].[I:22][c:23]1[cH:24][c:25]2[cH:26][cH:27][n:28]([Si:32]([CH:33]([CH3:34])[CH3:35])([CH:36]([CH3:37])[CH3:38])[CH:39]([CH3:40])[CH3:41])[c:29]2[cH:30][cH:31]1.[Zn:48]>>[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH:19]([c:23]2[cH:24][c:25]3[cH:26][cH:27][n:28]([Si:32]([CH:33]([CH3:34])[CH3:35])([CH:36]([CH3:37])[CH3:38])[CH:39]([CH3:40])[CH3:41])[c:29]3[cH:30][cH:31]2)[CH2:20]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9585383db17e4eabb68587d828b399a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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