Tetrahydrofuran → Isoquinoline-3-carboxaldehyde

HRID 950276Notes

Reaction equation

HRID 950276 reaction equation
[CH3:15][CH:16]([CH2:17][AlH:18][CH2:19][CH:20]([CH3:21])[CH3:22])[CH3:23].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[cH:14]1.[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[O:2]=[CH:3][c:5]1[n:6][cH:7][c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[cH:14]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 14487Diisobutylaluminum hydrideHCID 725374Methyl 3-isoquinolinecarboxylate

Product 1

HCID 231555Isoquinoline-3-carboxaldehyde

Sources & evidence

ORD record
ord-f621e33d049f4ab4bf14ace7543960c0
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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