Hydrochloric Acid → Isopropyl 4-bromopiperidine-1-carboxylate

HRID 950494Notes

Reaction equation

HRID 950494 reaction equation
[Br:2][CH:3]1[CH2:4][CH2:5][NH:6][CH2:7][CH2:8]1.[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[CH:9]([N:10]([CH:11]([CH3:12])[CH3:13])[CH2:14][CH3:15])([CH3:16])[CH3:17].[Cl:18][C:19](=[O:20])[O:21][CH:22]([CH3:23])[CH3:24].[Cl:25][CH2:26][Cl:27].[ClH:1]>>[Br:2][CH:3]1[CH2:4][CH2:5][N:6]([C:19](=[O:20])[O:21][CH:22]([CH3:23])[CH3:24])[CH2:7][CH2:8]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 1140TolueneHCID 6344DichloromethaneHCID 7917Isopropyl chloroformateHCID 81531DiisopropylethylamineHCID 4209294-Bromopiperidine

Product 1

HCID 68842564Isopropyl 4-bromopiperidine-1-carboxylate

Sources & evidence

ORD record
ord-31db69a59fa54608a0f020053a37d339
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…