HRID950765

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID769

Bicarbonate Ion

CHO3-

HCID923

Sodium ion

Na+

2 次

HCID6228

Dimethylformamide

C3H7NO

HCID8857

Ethyl Acetate

C4H8O2

HCID122573

3,5-Bis(trifluoromethyl)benzyl bromide

C9H5BrF6

HCID166653

Hydride

H-

HCID67087263

5-Bromo-N-[[2-fluoro-5-(trifluoromethyl)phenyl]methyl]-2-pyrimidinamine

C12H8BrF4N3

PRODUCTS

产物

HCID86626777

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-4c69f1660d55484591677d1eb4bac5ae
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[Br:1][c:2]1[cH:3][n:4][c:5]([NH:8][CH2:9][c:10]2[c:11]([F:20])[cH:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]2)[n:6][cH:7]1.[Br:23][CH2:24][c:25]1[cH:26][c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1.[C:39](=[O:40])([OH:41])[O-:42].[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[CH3:49][CH2:50][O:51][C:52](=[O:53])[CH3:54].[H-:21].[Na+:22].[Na+:43]>>[Br:1][c:2]1[cH:3][n:4][c:5]([N:8]([CH2:9][c:10]2[c:11]([F:20])[cH:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]2)[CH2:24][c:25]2[cH:26][c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]2)[n:6][cH:7]1