Water → Tert-butyl 4-[(1,3-dioxoisoindol-2-yl)methyl]-3-hydroxypiperidine-1-carboxylate

HRID 95119Notes

Reaction equation

HRID 95119 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:20])[CH:11]([CH2:14][O:15][S:16]([CH3:17])(=[O:18])=[O:19])[CH2:12][CH2:13]1.[C:21]1(=[O:31])[c:22]2[c:23]([cH:27][cH:28][cH:29][cH:30]2)[C:24](=[O:26])[NH:25]1.[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[K:32].[OH2:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:20])[CH:11]([CH2:14][N:25]2[C:21](=[O:31])[c:22]3[c:23]([cH:27][cH:28][cH:29][cH:30]3)[C:24]2=[O:26])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 6809PhthalimideHCID 5462222PotassiumHCID 56992981HCID 56992981, compound

Product 1

HCID 70075562Tert-butyl 4-[(1,3-dioxoisoindol-2-yl)methyl]-3-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-3a2ee3d851cc4f5c9c83854ea479b403
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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