Tetrahydrofuran → (4-Methyl-2-morpholinyl)methanol

HRID 952164Notes

Reaction equation

HRID 952164 reaction equation
[Al+3:17].[C:1]([O:2][C:6](=[O:3])[N:8]1[CH2:9][CH:10]([CH2:14][OH:15])[O:11][CH2:12][CH2:13]1)([CH3:4])([CH3:5])[CH3:7].[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[H-:16].[H-:19].[H-:20].[H-:21].[Li+:18]>>[CH3:6][N:8]1[CH2:9][CH:10]([CH2:14][OH:15])[O:11][CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 5201202tert-Butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Product 1

HCID 13949887(4-Methyl-2-morpholinyl)methanol

Sources & evidence

ORD record
ord-2611936a26e84b2f9b4b2d09a3f839ce
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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