Hydrochloric Acid → methyl 1-benzoylpyrrolidine-2-carboxylate

HRID 952267Notes

Reaction equation

HRID 952267 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH3:11][O:12][C:13]([CH:14]1[NH:15][CH2:16][CH2:17][CH2:18]1)=[O:19].[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[Cl:27][CH2:28][Cl:29].[ClH:10]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[N:15]1[CH:14]([C:13]([O:12][CH3:11])=[O:19])[CH2:18][CH2:17][CH2:16]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 94239Methyl DL-prolinate

Product 1

HCID 338198methyl 1-benzoylpyrrolidine-2-carboxylate

Sources & evidence

ORD record
ord-9ecc9bc5c6ba4576962dbf93f1914fa6
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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