2,6-Lutidine → 4-Chloro-2,6-bis-trifluoromethyl-nicotinic acid ethyl ester
Reaction equation
[F:1][C:2]([c:3]1[n:4][c:5]([C:15]([F:16])([F:17])[F:18])[cH:6][c:7]([OH:14])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:19])[F:20].[P:29]([Cl:30])([Cl:31])([Cl:32])=[O:33].[n:21]1[c:22]([CH3:23])[cH:24][cH:25][cH:26][c:27]1[CH3:28]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:15]([F:16])([F:17])[F:18])[cH:6][c:7]([Cl:31])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:19])[F:20]Participants
4
Sources & evidence
- ORD record
- ord-b779af7d899d449198b0db4d7aa029c0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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