HRID952654

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1049

Pyridine

C5H5N

HCID8028

Tetrahydrofuran

C4H8O

HCID81531

Diisopropylethylamine

C8H19N

HCID2734844

2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

C9H18ClN2OP

结构：Cc1cn(C2CC(O)C(CSCc3c4ccccc4cc4ccccc34)O2)c(=O)[nH]c1=O

HCID178429994

未命名化合物

PRODUCTS

生成物

结构：Cc1cn(C2CC(OP(OCCC#N)N(C(C)C)C(C)C)C(CSCc3c4ccccc4cc4ccccc34)O2)c(=O)[nH]c1=O

HCID178430003

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ee6c5fdbbde2489984d5e93ea61edb71
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH:39]([N:40]([CH:41]([CH3:42])[CH3:43])[CH2:44][CH3:45])([CH3:46])[CH3:47].[CH:48]([CH3:49])([CH3:50])[N:51]([P:52]([O:53][CH2:54][CH2:55][C:56]#[N:57])[Cl:58])[CH:59]([CH3:60])[CH3:61].[O:62]1[CH2:63][CH2:64][CH2:65][CH2:66]1.[cH:1]1[cH:2][cH:3][cH:4][c:5]2[cH:6][c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]3[c:13]([CH2:15][S:16][CH2:17][CH:18]3[CH:19]([OH:32])[CH2:20][CH:21]([n:23]4[c:24](=[O:25])[nH:26][c:27](=[O:28])[c:29]([CH3:30])[cH:31]4)[O:22]3)[c:14]12.[cH:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1>>[cH:1]1[cH:2][cH:3][cH:4][c:5]2[cH:6][c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]3[c:13]([CH2:15][S:16][CH2:17][CH:18]3[CH:19]([O:32][P:52]([N:51]([CH:48]([CH3:49])[CH3:50])[CH:59]([CH3:60])[CH3:61])[O:53][CH2:54][CH2:55][C:56]#[N:57])[CH2:20][CH:21]([n:23]4[c:24](=[O:25])[nH:26][c:27](=[O:28])[c:29]([CH3:30])[cH:31]4)[O:22]3)[c:14]12