Tetrahydrofuran → Ethyl 2-(4-chloropyridin-3-ylamino)-2-oxoacetate

HRID 952669Notes

Reaction equation

HRID 952669 reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cl:16][C:17]([C:18](=[O:19])[O:20][CH2:21][CH3:22])=[O:23].[Cl:1][c:2]1[c:3]([NH2:8])[cH:4][n:5][cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([NH:8][C:17]([C:18](=[O:19])[O:20][CH2:21][CH3:22])=[O:23])[cH:4][n:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 20884Ethoxalyl chlorideHCID 5819323-Amino-4-chloropyridine

Product 1

HCID 67306384Ethyl 2-(4-chloropyridin-3-ylamino)-2-oxoacetate

Sources & evidence

ORD record
ord-9e0b14f3ff664babaaa9f3e0f174b4bc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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