Tetrahydrofuran → 1'-pentylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

HRID 95275Notes

Reaction equation

HRID 95275 reaction equation
[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[O:20]=[C:21]([O:22][CH2:23][CH3:24])[N:25]=[N:26][C:27]([O:28][CH2:29][CH3:30])=[O:31].[OH:32][c:33]1[c:34]([C:42]2([CH2:57][OH:58])[C:43](=[O:56])[N:44]([CH2:51][CH2:52][CH2:53][CH2:54][CH3:55])[c:45]3[n:46][cH:47][cH:48][cH:49][c:50]32)[cH:35][c:36]2[c:37]([cH:41]1)[O:38][CH2:39][O:40]2.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[O:32]1[c:33]2[c:34]([cH:35][c:36]3[c:37]([cH:41]2)[O:38][CH2:39][O:40]3)[C:42]2([C:43](=[O:56])[N:44]([CH2:51][CH2:52][CH2:53][CH2:54][CH3:55])[c:45]3[n:46][cH:47][cH:48][cH:49][c:50]32)[CH2:57]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 119628123-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-1-pentyl-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Product 1

HCID 118483031'-pentylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Sources & evidence

ORD record
ord-7f4064cdaaed41579faa084285237b09
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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