Acetate → 2-(4-fluoro-phenyl)-cyclopropanecarboxylic Acid Ethyl Ester

HRID 952770Notes

Reaction equation

HRID 952770 reaction equation
[CH3:22][CH2:23][O:24][C:25](=[O:26])[CH3:27].[CH:18]([Cl:19])([Cl:20])[Cl:21].[Cu:28][I:29].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[CH2:7])[cH:8][cH:9]1.[N+:10](=[N-:11])=[CH:12][C:13](=[O:14])[O:15][CH2:16][CH3:17].[O-:31][C:32]([CH3:33])=[O:34].[O-:35][C:36]([CH3:37])=[O:38].[Pd+2:30]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]2[CH2:7][CH:12]2[C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:8][cH:9]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6212ChloroformHCID 8857Ethyl AcetateHCID 12192Ethyl diazoacetateHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 678834-FluorostyreneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 232682772-(4-fluoro-phenyl)-cyclopropanecarboxylic Acid Ethyl Ester

Sources & evidence

ORD record
ord-7e437c13005a40b2b46d4c1f604c9541
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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