Acetonitrile → 2-Amino-3-cyano-4-methyl-5-[(4-trifluoromethylphenyl)ethynyl]pyridine
Reaction equation
[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:31][C:32]#[N:33].[Cu:34][I:35].[F:13][C:14]([c:15]1[cH:16][cH:17][c:18]([I:21])[cH:19][cH:20]1)([F:22])[F:23].[NH2:1][c:2]1[n:3][cH:4][c:5]([C:11]#[CH:12])[c:6]([CH3:10])[c:7]1[C:8]#[N:9]>>[NH2:1][c:2]1[n:3][cH:4][c:5]([C:11]#[C:12][c:18]2[cH:17][cH:16][c:15]([C:14]([F:13])([F:22])[F:23])[cH:20][cH:19]2)[c:6]([CH3:10])[c:7]1[C:8]#[N:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-48e4fd45068c4d219aedc35c6b19aacb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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