Sodium ion → Tert-butyl 2,2-diphenyl-5-(phenylmethoxymethyl)morpholine-4-carboxylate

HRID 952840Notes

Reaction equation

HRID 952840 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][O:10][C:11]([CH2:12][I:13])([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[CH2:26][O:27][CH2:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)=[O:35].[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[H-:36].[Na+:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]1[CH:8]([CH2:26][O:27][CH2:28][c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:9][O:10][C:11]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:12]1)=[O:35]

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 166653HydrideHCID 77514010tert-butyl N-[1-(2-iodo-1,1-diphenylethoxy)-3-phenylmethoxypropan-2-yl]carbamate

Product 1

HCID 68561086Tert-butyl 2,2-diphenyl-5-(phenylmethoxymethyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-e4f756c586c8448dbf08086b2f0d6c8b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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