Sodium ion → 4-(7-Methoxy-thiazolo[5,4-d]pyrimidin-2-ylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester

HRID 952864Notes

Reaction equation

HRID 952864 reaction equation
[C:24]([CH3:25])([CH3:26])([CH3:27])[O:28][C:29](=[O:30])[N:31]1[CH2:32][CH2:33][N:34]([C:37](=[O:38])[Cl:39])[CH2:35][CH2:36]1.[CH3:1][O:2][c:3]1[c:4]2[c:5]([n:6][cH:7][n:8]1)[s:9][c:10]([NH2:12])[n:11]2.[CH:15]([N:16]([CH2:17][CH3:18])[CH:19]([CH3:20])[CH3:21])([CH3:22])[CH3:23].[H-:13].[Na+:14].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[CH3:1][O:2][c:3]1[c:4]2[c:5]([n:6][cH:7][n:8]1)[s:9][c:10]([NH:12][C:37]([N:34]1[CH2:33][CH2:32][N:31]([C:29]([O:28][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:30])[CH2:36][CH2:35]1)=[O:38])[n:11]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 166653HydrideHCID 11334154Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylateHCID 574765977-Methoxy-[1,3]thiazolo[5,4-d]pyrimidin-2-amine

Product 1

HCID 590119304-(7-Methoxy-thiazolo[5,4-d]pyrimidin-2-ylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-426865e95f044a2b90af58e3287bd27e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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