Hydrochloric Acid → 4-(2-Methylpyrrolidin-1-yl)piperidine

HRID 952871Notes

Reaction equation

HRID 952871 reaction equation
[C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])(=[O:20])[N:21]1[CH2:22][CH2:23][CH:24]([N:27]2[CH:28]([CH3:32])[CH2:29][CH2:30][CH2:31]2)[CH2:25][CH2:26]1.[CH3:3][CH:4]1[CH2:5][CH2:6][CH2:7][N:8]1[CH:9]1[CH2:10][CH2:11][NH:12][CH2:13]1.[CH3:44][CH:45]1[CH2:46][CH2:47][CH2:48][NH:49]1.[ClH:1].[ClH:2].[O-:33][S:34]([c:35]1[cH:36][cH:37][c:38]([CH3:39])[cH:40][cH:41]1)(=[O:42])=[O:43]>>[NH:21]1[CH2:22][CH2:23][CH:24]([N:27]2[CH:28]([CH3:32])[CH2:29][CH2:30][CH2:31]2)[CH2:25][CH2:26]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 130032-MethylpyrrolidineHCID 85570p-ToluenesulfonateHCID 534010602-Methyl-1-pyrrolidin-3-ylpyrrolidineHCID 57445899Tert-butyl 4-(2-methylpyrrolidin-1-yl)piperidine-1-carboxylate

Product 1

HCID 574458864-(2-Methylpyrrolidin-1-yl)piperidine

Sources & evidence

ORD record
ord-ab1d06d62946408f97f86609d1e4782f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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