Hydrochloric Acid → 4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[2,3-d]pyrimidine-4,7-diamine

HRID 953028Notes

Reaction equation

HRID 953028 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12][c:13]([F:16])[cH:14][cH:15]3)[cH:17][cH:18][cH:19]1.[CH3:20][NH:21][CH3:22].[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:31][CH2:32][OH:33].[ClH:23]>>[Br:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12][c:13]([N:21]([CH3:20])[CH3:22])[cH:14][cH:15]3)[cH:17][cH:18][cH:19]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 674DimethylamineHCID 702EthanolHCID 8471TriethylamineHCID 5328268N-(3-bromophenyl)-7-fluoropyrido[2,3-d]pyrimidin-4-amine

Product 1

HCID 53282704-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[2,3-d]pyrimidine-4,7-diamine

Sources & evidence

ORD record
ord-beb95aaf07314c5abcc61302b45222c7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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