Chloride → 7-fluoro-6-hydrazino-4-propargyl-2H-1,4-benzoxazin-3-one

HRID 953365Notes

Reaction equation

HRID 953365 reaction equation
[Cl-:21].[ClH:24].[N:17]([O-:18])=[O:19].[NH2:1][c:2]1[c:3]([F:16])[cH:4][c:5]2[c:6]([cH:15]1)[N:7]([CH2:12][C:13]#[CH:14])[C:8](=[O:11])[CH2:9][O:10]2.[Na+:20].[Na+:23].[OH-:22]>>[NH:1]([c:2]1[c:3]([F:16])[cH:4][c:5]2[c:6]([cH:15]1)[N:7]([CH2:12][C:13]#[CH:14])[C:8](=[O:11])[CH2:9][O:10]2)[NH2:17]

Participants

7

Reactant 6

HCID 312ChlorideHCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 946NitriteHCID 961HydroxideHCID 111603236‐Amino‐7‐fluoro‐4‐(prop‐2‐yn‐1‐yl)‐3,4‐dihydro‐2H‐ 1,4‐benzoxazin‐3‐one

Product 1

HCID 145179487-fluoro-6-hydrazino-4-propargyl-2H-1,4-benzoxazin-3-one

Sources & evidence

ORD record
ord-2890e7619f6e42e8b52d200cfe6b4959
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…