Phthalimide → tert-Butyl 3-(4-bromophenyl)-1-(1,3-dioxoisoindolin-2-yl)propan-2-ylcarbamate
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]([CH2:10][OH:11])[NH:12][C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[cH:6][cH:7]1.[O:20]=[C:21]1[NH:22][C:23](=[O:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]21.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]([CH2:10][N:22]2[C:21](=[O:20])[c:30]3[c:25]([cH:26][cH:27][cH:28][cH:29]3)[C:23]2=[O:24])[NH:12][C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-8137f445480b40c0a1f4e7213134503f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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