Dimethylformamide → Pyridine, 2,6-dichloro-3-(chloromethyl)-

HRID 953580Notes

Reaction equation

[CH3:18][N:19]([CH3:20])[CH:21]=[O:22].[Cl:12][C:13]([C:14]([Cl:15])=[O:16])=[O:17].[Cl:1][c:2]1[c:3]([C:4]([OH:5])=[O:6])[cH:7][cH:8][c:9]([Cl:11])[n:10]1.[Cl:23][CH2:24][Cl:25]>>[Cl:1][c:2]1[c:3]([CH2:4][Cl:12])[cH:7][cH:8][c:9]([Cl:11])[n:10]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6344Dichloromethane

HCID 65578Oxalyl chloride

HCID 8540472,6-Dichloronicotinic acid

Product 1

HCID 6451791Pyridine, 2,6-dichloro-3-(chloromethyl)-

Sources & evidence

ORD record: ord-6644791678424cfe9e0fad9df0a12e95
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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