Potassium Cation → 2-((2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)isoindoline-1,3-dione

HRID 953583Notes

Reaction equation

HRID 953583 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5]2[n:6][c:7]([Cl:18])[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[s:11]1.[K+:19].[K+:20].[O-:21][C:22]([O-:23])=[O:24].[O:25]=[C:26]1[NH:27][C:28](=[O:29])[c:30]2[cH:31][cH:32][cH:33][cH:34][c:35]21.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[CH2:2]([c:3]1[cH:4][c:5]2[n:6][c:7]([Cl:18])[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[s:11]1)[N:27]1[C:26](=[O:25])[c:35]2[c:30]([cH:31][cH:32][cH:33][cH:34]2)[C:28]1=[O:29]

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 6809PhthalimideHCID 19660Carbonate IonHCID 461807264-(6-(Bromomethyl)-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine

Product 1

HCID 595931082-((2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)isoindoline-1,3-dione

Sources & evidence

ORD record
ord-49a93bda295b46a99d6cf7ed8223c635
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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