Methanol → 6-[[4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-1-ethoxycarbonyl-6-methoxy-2-methyl-3,4-dihydro-2H-quinolin-7-yl]oxy]hexanoic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH:7]([CH3:49])[CH2:8][CH:9]([N:29]([C:30](=[O:31])[O:32][CH3:33])[CH2:34][c:35]2[cH:36][c:37]([C:45]([F:46])([F:47])[F:48])[cH:38][c:39]([C:41]([F:42])([F:43])[F:44])[cH:40]2)[c:10]2[cH:11][c:12]([O:27][CH3:28])[c:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26])[cH:14][c:15]21.[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[CH3:57][OH:58].[Li+:50].[OH-:51]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH:7]([CH3:49])[CH2:8][CH:9]([N:29]([C:30](=[O:31])[O:32][CH3:33])[CH2:34][c:35]2[cH:36][c:37]([C:45]([F:46])([F:47])[F:48])[cH:38][c:39]([C:41]([F:42])([F:43])[F:44])[cH:40]2)[c:10]2[cH:11][c:12]([O:27][CH3:28])[c:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22](=[O:23])[OH:24])[cH:14][c:15]21Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e2164f130a0849ed887824098d60fb1d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…