Chloride → 4-Chloro-4'-isopropylbenzophenone

HRID 95387Notes

Reaction equation

HRID 95387 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[c:10]2[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]2)[cH:6][cH:7]1.[CH:18]([CH3:19])([CH3:20])[Mg+:21].[Cl-:17].[Ni:27]([Cl:28])[Cl:29].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1.[c:30]1([P:31]([CH:32]([P:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[CH2:46][CH3:47])[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1>>[c:2]1([CH:18]([CH3:19])[CH3:20])[cH:3][cH:4][c:5]([C:8](=[O:9])[c:10]2[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 24385Nickel DichlorideHCID 2756868(4-Bromophenyl)(4-chlorophenyl)methanoneHCID 129081181-Diphenylphosphanylpropyl(diphenyl)phosphaneHCID 178461726HCID 178461726, compound

Product 1

HCID 27576234-Chloro-4'-isopropylbenzophenone

Sources & evidence

ORD record
ord-7b2de99ad88f4304a48ec22545d04616
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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