HRID953931

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7237

o-Xylene

C8H10

HCID11776

Triphenylphosphine

C18H15P

2 次

HCID24290

未命名化合物

HCID11128458

Trimethyl(4-pyridyl)tin

C8H13NSn

结构：COc1ccc(Br)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)nc1

HCID22349594

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(-c2ccncc2)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)nc1

HCID10202062

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e07f0b855e5b4da29497103561073639
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:1][c:2]1[cH:3][cH:4][c:5]([O:25][CH3:26])[c:6]([C:8](=[O:9])[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]3)[cH:14][cH:15]2)[cH:7]1.[CH3:27][Sn:28]([c:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1)([CH3:35])[CH3:36].[Pd:45]([Cl:46])[Cl:47].[c:37]1([CH3:38])[c:39]([CH3:40])[cH:41][cH:42][cH:43][cH:44]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1.[c:67]1([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[cH:81][cH:82][cH:83][cH:84][cH:85]1>>[c:2]1(-[c:29]2[cH:30][cH:31][n:32][cH:33][cH:34]2)[cH:3][cH:4][c:5]([O:25][CH3:26])[c:6]([C:8](=[O:9])[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]3)[cH:14][cH:15]2)[cH:7]1