HRID954109

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID795

Imidazole

C3H4N2

HCID962

Water

H2O

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID8857

Ethyl acetate

C4H8O2

HCID28928

Chloro(1,1-dimethylethyl)dimethylsilane

C6H15ClSi

结构：Cc1c(NC(C(=O)NCC(=O)c2ccccc2)C(C)O)ccc(C#N)c1Cl

HCID178430574

未命名化合物

PRODUCTS

生成物

结构：Cc1c(NC(C(=O)NCC(=O)c2ccccc2)C(C)O[Si](C)(C)C(C)(C)C)ccc(C#N)c1Cl

HCID178430575

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-eecb5948bb76433f9be577f2e99273a2
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[C:38]([CH3:39])([CH3:40])([CH3:41])[Si:42]([CH3:43])([CH3:44])[Cl:45].[CH3:46][CH2:47][O:48][C:49]([CH3:50])=[O:51].[Cl:1][c:2]1[c:3]([CH3:27])[c:4]([NH:10][CH:11]([C:12](=[O:13])[NH:14][CH2:15][C:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)=[O:23])[CH:24]([CH3:25])[OH:26])[cH:5][cH:6][c:7]1[C:8]#[N:9].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[OH2:52].[nH:33]1[cH:34][cH:35][n:36][cH:37]1>>[Cl:1][c:2]1[c:3]([CH3:27])[c:4]([NH:10][CH:11]([C:12](=[O:13])[NH:14][CH2:15][C:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)=[O:23])[CH:24]([CH3:25])[O:26][Si:42]([C:38]([CH3:39])([CH3:40])[CH3:41])([CH3:43])[CH3:44])[cH:5][cH:6][c:7]1[C:8]#[N:9]