Acetate → Tert-butyl 2-(2-phenylpyrimidin-5-yl)thiazole-4-carboxylate
Reaction equation
[Br:61][c:62]1[cH:63][n:64][c:65](-[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[n:66][cH:67]1.[C:1](=[O:2])([O-:3])[O-:4].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[c:14]1[n:15][cH:16][s:17][cH:18]1.[Cs+:5].[Cs+:6].[O-:80][C:81]([CH3:82])=[O:83].[O-:84][C:85]([CH3:86])=[O:87].[O:74]=[CH:75][N:76]([CH3:77])[CH3:78].[Pd+2:79].[c:19]1([P:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[c:28]3[c:52]([cH:53][cH:54][cH:55]2)[C:49]([CH3:50])([CH3:51])[c:31]2[c:30]([c:35]([P:36]([c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[c:43]4[cH:44][cH:45][cH:46][cH:47][cH:48]4)[cH:34][cH:33][cH:32]2)[O:29]3)[cH:56][cH:57][cH:58][cH:59][cH:60]1>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[c:14]1[n:15][c:16](-[c:62]2[cH:63][n:64][c:65](-[c:68]3[cH:69][cH:70][cH:71][cH:72][cH:73]3)[n:66][cH:67]2)[s:17][cH:18]1Participants
9
Reactant 8
HCID 175Acetate2×
HCID 6228Dimethylformamide
HCID 19660Carbonate Ion
HCID 104967Cesium cation2×
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)
HCID 143877455-Bromo-2-phenylpyrimidine
HCID 16744294Tert-butyl 1,3-thiazole-4-carboxylateProduct 1
Sources & evidence
- ORD record
- ord-079a0534371f49aca81ddc55f452bc11
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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