Tetrahydrofuran → 2-(5-Methyl-2-phenyl-4-oxazolylmethoxy)-4-pyridylmethanol

HRID 954641Notes

Reaction equation

HRID 954641 reaction equation
[Al+3:27].[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:15]2[n:16][cH:17][cH:18][c:19]([C:21](=[O:22])[O:23][CH3:24])[cH:20]2)[n:4][c:5](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[o:6]1.[H-:25].[H-:28].[H-:29].[H-:30].[Li+:26].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH2:21][OH:22])[cH:20]2)[n:4][c:5](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[o:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 17861336Methyl 2-(5-methyl-2-phenyl-4-oxazolyl)methoxy-4-pyridinecarboxylate

Product 1

HCID 178613752-(5-Methyl-2-phenyl-4-oxazolylmethoxy)-4-pyridylmethanol

Sources & evidence

ORD record
ord-734c4a9e0a63464c8a2f8a49adf2e972
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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