Tetrahydrofuran → 5-Benzoyloxy-3-chloro-1-iodo-2-[3-(5-trifluoromethylpyrid-2-yloxy)propyloxy]benzene

HRID 954882Notes

Reaction equation

HRID 954882 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[O:9][c:10]1[cH:11][c:12]([Cl:18])[c:13]([OH:17])[c:14]([I:16])[cH:15]1.[F:19][C:20]([c:21]1[cH:22][cH:23][c:24]([O:27][CH2:28][CH2:29][CH2:30][OH:31])[n:25][cH:26]1)([F:32])[F:33].[O:53]=[C:54]([O:55][CH2:56][CH3:57])[N:58]=[N:59][C:60]([O:61][CH2:62][CH3:63])=[O:64].[O:65]1[CH2:66][CH2:67][CH2:68][CH2:69]1.[c:34]1([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:48][cH:49][cH:50][cH:51][cH:52]1>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[O:9][c:10]1[cH:11][c:12]([Cl:18])[c:13]([O:17][CH2:30][CH2:29][CH2:28][O:27][c:24]2[cH:23][cH:22][c:21]([C:20]([F:19])([F:32])[F:33])[cH:26][n:25]2)[c:14]([I:16])[cH:15]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 112067993-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}propan-1-olHCID 223186275-Benzoyloxy-3-chloro-2-hydroxy-1-iodobenzene

Product 1

HCID 223186095-Benzoyloxy-3-chloro-1-iodo-2-[3-(5-trifluoromethylpyrid-2-yloxy)propyloxy]benzene

Sources & evidence

ORD record
ord-ac7822a1ede4437a9f631f74c5253502
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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