Triethylamine → 1-(trans-4-Pentylcyclohexyl)-2-(4-trifluoromethylphenyl)acetylene

HRID 954883Notes

Reaction equation

HRID 954883 reaction equation
[CH2:1]([CH2:2][CH2:3][CH2:4][CH3:5])[CH:6]1[CH2:7][CH2:8][CH:9]([C:12]#[CH:13])[CH2:10][CH2:11]1.[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[Cu:25][I:26].[F:14][C:15]([c:16]1[cH:17][cH:18][c:19]([Br:22])[cH:20][cH:21]1)([F:23])[F:24]>>[CH2:1]([CH2:2][CH2:3][CH2:4][CH3:5])[CH:6]1[CH2:7][CH2:8][CH:9]([C:12]#[C:13][c:19]2[cH:18][cH:17][c:16]([C:15]([F:14])([F:23])[F:24])[cH:21][cH:20]2)[CH2:10][CH2:11]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 67872Benzene, 1-bromo-4-(trifluoromethyl)-HCID 143657611-Ethynyl-4-pentylcyclohexane

Product 1

HCID 199851621-(trans-4-Pentylcyclohexyl)-2-(4-trifluoromethylphenyl)acetylene

Sources & evidence

ORD record
ord-793800216a4f4a0ba9ab4d40a3c23546
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…