Benzene → 5-Bromo-2-(2,2-dimethylpropionylamino)-3-hydroxybenzoic Acid

HRID 955099Notes

Reaction equation

HRID 955099 reaction equation
[C:19]([C:20]([CH3:21])([CH3:22])[CH3:23])(=[O:24])[Cl:25].[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[ClH:26].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([Br:12])[cH:9][c:10]1[OH:11].[cH:13]1[cH:14][cH:15][n:16][cH:17][cH:18]1.[cH:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[NH:1]([c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([Br:12])[cH:9][c:10]1[OH:11])[C:19]([C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24]

Participants

7

Reactant 6

HCID 241BenzeneHCID 313Hydrochloric AcidHCID 1049PyridineHCID 8857Ethyl AcetateHCID 62493Pivaloyl chlorideHCID 217551432-Amino-5-bromo-3-hydroxybenzoic Acid

Product 1

HCID 685848145-Bromo-2-(2,2-dimethylpropionylamino)-3-hydroxybenzoic Acid

Sources & evidence

ORD record
ord-7330afc82b5b4208ba85734d3846350c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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