Tetrahydrofuran → (3-benzyloxy-1-phenyl-1H-pyrazol-5-yl)methanol

HRID 955262Notes

Reaction equation

HRID 955262 reaction equation
[Al+3:26].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[n:10][n:11](-[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:12]([C:14](=[O:15])[O:16][CH3:17])[cH:13]1.[H-:24].[H-:27].[H-:28].[H-:29].[Li+:25].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[n:10][n:11](-[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:12]([CH2:14][OH:15])[cH:13]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 22930789methyl 3-benzyloxy-1-phenyl-1H-pyrazole-5-carboxylate

Product 1

HCID 22930692(3-benzyloxy-1-phenyl-1H-pyrazol-5-yl)methanol

Sources & evidence

ORD record
ord-a0107e4e8ee943c18c162b825836494e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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