Catechol → 2-(Difluoromethoxy)phenol

HRID 955456Notes

Reaction equation

HRID 955456 reaction equation
[Cl:1][CH:2]([F:3])[F:4].[Na+:14].[Na+:21].[Na+:22].[O:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1.[OH-:13].[OH2:23].[S:15]([S:16]([O-:17])=[O:18])([O-:19])=[O:20].[c:5]1([OH:6])[c:7]([OH:8])[cH:9][cH:10][cH:11][cH:12]1>>[CH:2]([F:3])([F:4])[O:6][c:5]1[c:7]([OH:8])[cH:9][cH:10][cH:11][cH:12]1

Participants

8

Reactant 7

HCID 289CatecholHCID 923Sodium ion3×HCID 961HydroxideHCID 962WaterHCID 1086DithioniteHCID 6372ChlorodifluoromethaneHCID 312751,4-Dioxane

Product 1

HCID 27741212-(Difluoromethoxy)phenol

Sources & evidence

ORD record
ord-f2f8fda83a574d9f8a88af5b29bd979d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…