Dimethyl Sulfoxide → 1-(3-Chlorophenoxy)-4-(4-pyridylmethyl)phthalazine

HRID 955492Notes

Reaction equation

HRID 955492 reaction equation
[CH3:34][S:35]([CH3:36])=[O:37].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:1][c:2]1[n:3][n:4][c:5]([CH2:12][c:13]2[cH:14][cH:15][n:16][cH:17][cH:18]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[K+:19].[K+:20].[O-:21][C:22]([O-:23])=[O:24].[OH2:33].[OH:25][c:26]1[cH:27][cH:28][cH:29][c:30]([Cl:31])[cH:32]1>>[c:2]1([O:25][c:26]2[cH:27][cH:28][cH:29][c:30]([Cl:31])[cH:32]2)[n:3][n:4][c:5]([CH2:12][c:13]2[cH:14][cH:15][n:16][cH:17][cH:18]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 79333-ChlorophenolHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 19446091-Chloro-4-(4-pyridinylmethyl)phthalazine

Product 1

HCID 227420201-(3-Chlorophenoxy)-4-(4-pyridylmethyl)phthalazine

Sources & evidence

ORD record
ord-d002b1778c0840ffa4493fb9cc0d2fe3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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